Tatooine is a real place, or at least it is stitched together from about eight of them, all in southern Tunisia and none of them within easy reach of each other. That single geographic fact decides almost everything about which tour you should book, and it is the thing the listings themselves are worst at explaining.
Start with the map. The locations fall into two clusters separated by roughly five hours of road. The eastern cluster sits inland from Djerba: Matmata, where Hotel Sidi Driss still has the sunken courtyard used as the Lars homestead interior, and the ksour around Tataouine, where Ksar Hadada and Ksar Ouled Soltane both played the slave quarters young Anakin grew up in. The western cluster sits beyond Tozeur: Mos Espa itself, standing out in the open desert near Ong Jmal, with the Chott el Djerid salt flat and the Sidi Bouhlel canyon nearby.
No day trip covers both clusters. Tours that claim to are selling you a two-day itinerary or a lot of windscreen. If you want the whole map you need two bases or a multi-day run, and the honest version of that is which tour is right for you, which sets the options against each other properly.
What each site actually gives you
Mos Espa is the one people picture. It was built for The Phantom Menace in 1997 and left standing when the crew went home, and the dry climate has kept it up far longer than anyone intended. You can walk the street, look into the domes, and climb the dune behind it. It is not maintained to museum standard and the sand from the Chott el Gharsa is slowly taking it back, which is either a disappointment or the whole atmosphere depending on what you came for. Most Tozeur itineraries give it around thirty minutes.
Hotel Sidi Driss is the opposite kind of visit. It is a working hotel in Matmata, dug down into the ground the way houses there have always been, and the courtyard where Luke argued with his uncle is now a dining room with set dressing still on the walls from the 2002 shoot. The visit is short and indoors and it costs an entry fee, which some Djerba tours include and others quietly leave off.
The ksour are the ones that surprise people. Ksar Hadada and Ksar Ouled Soltane are genuine fortified granaries, centuries old before a film crew ever saw them, built as honeycombs of vaulted storage cells stacked three and four high around a courtyard. They were not dressed up much for the camera because they did not need to be. Ouled Soltane in particular photographs better than anything else in the south.
Chenini gets bundled onto almost every Tataouine itinerary and is not a filming location at all. It is a Berber village built into a cliff, still inhabited, reached on foot up uneven ground. It is also the stop that reviewers mention most often when they describe a day as worthwhile, which is worth knowing before you dismiss it as filler.
Departure towns, and why your hotel decides this
Almost every tour here is a pickup tour. You book a date, hand over your hotel name, and a driver collects you somewhere between five thirty and seven in the morning. That makes your accommodation the first filter, not the itinerary.
From Djerba and Zarzis you can reach Matmata, Chenini and the Tataouine ksour, and the market for those runs is crowded enough that prices sit around fifty to seventy dollars for a full day with lunch. From Tozeur or Nefta you reach Mos Espa, Ong Jmal and the mountain oases at Chebika, Tamerza and Mides, usually in a private vehicle and usually for more money, because the operators there sell smaller groups. From Tunis nothing is close, and the sensible options are two-day trips that pick up El Jem and Kairouan on the way through.
What the days are actually like
Long. Twelve hours is normal from Djerba, and the best-rated tours are not the ones that cram in an extra stop but the ones whose passengers say the driver did not rush them. Expect unsealed sand track for part of the route, a lunch that is included more often than not, and a back row of seats that reviewers of even five-star tours describe as punishing.
Two costs sit outside almost every ticket. Drinks with the included lunch are nearly always extra, and this is far and away the most common complaint left by people who otherwise loved their day. Camel rides and quad hire at the oases are sold on site for cash. Bring dinars.
Site entry fees are the variable worth checking line by line. A tour that includes entry to Sidi Driss, Ksar Hadada and Ksar Ouled Soltane is doing more for you than one priced ten dollars lower that leaves all three at the gate. The comparison table above lists what each option covers, and every tour page on this site sets out the inclusions and the exclusions as the operator states them.
If you want a shortlist rather than a survey: from the island, the full-day jeep safari to Ksar Ghilane and Matmata is the most-booked Star Wars tour in the country and covers its Sidi Driss entry. From the west, the Chebika, Mides and Mos Espa circuit is the highest-rated tour here with real review volume behind it, and the one that puts you inside the set.